Antibase 2010 scidex upgrade

Autore: Hartmut Laatsch  Casa Editrice: John Wiley & Sons  Anno Edizione: 2010 Edizione: 1 ISBN: 9783527327249 Pagine: NA Costo: 1.866,00 Euro (*) Materia: Biologia Animale e Vegetale - Ecosistemi Chimica farmaceutica e cosmesi Chimica Organica Microbiologia, Biochimica e Biotecnologie Lingua: Inglese

Progress in natural products chemistry today is progress in synthetic chemistry tomorrow. Structure determination of complex natural products delivers not only the most interesting, the most challenging targets for synthetic chemists, but is also the basis of new medical applications of the future. There is no doubt that natural product's isolation and structure identification is still one of the most important areas in chemistry. An army of scientists tries to discover with unlimited effort a limited number of natural metabolites: More than 170.000 natural products are known today, and every year are added about 700 new structures just only from micro-organisms. This gives raise to a major problem in natural product chemistry: It is unavoidable that certain common compounds are re-isolated again and again, a handicap which costs time and money, and is a steady source of avoidable frustration Antibase 2009, the Natural Compound Identifier, is a comprehensive database of more than 35,000 natural compounds from micro-organisms and higher fungi. The data in AntiBase have been collected from the primary and secondary literature and then carefully checked and validated. AntiBase includes descriptive data (molecular formula and mass, elemental composition, CAS registry number); physico-chemical data (melting point, optical rotation); spectroscopic data (UV, 13C-NMR, IR and mass spectra); biological data (pharmacological activity, toxicity); information on origin and isolation and a summary of literature sources